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Cardiorespiratory physiology in the bottlenose dolphin before, during, and after breath-holding and restraint.
- Call
- Office of Naval Research Contracts&Grants 2015.
- Investigador principal
- Dr. Andreas Fahlman
- Role
- Individual
- Year
- 2016
The proposed work is intended to evaluate cardiorespiratory (heart rate, stroke volume, systemic and pulmoarterial pressures, respiratory flow and expired gas composition) function in a small cetacean, the bottlenose dolphin, at rest, during apnea, during recovery from apnea and during and following a stressful situation. In addition, we will use these data to extract medical biomarkers from animals that are adapted to a range of extreme physiological challenges (e.g. hypoxia, ischemia/reperfusion, atelectasis). These biomarkers may provide valuable information for human clinical medicine.